Work Package 4 - Early HCC Detection
HCC-EDx with liquid biopsy-based methodologies (Work package 4) will look at lipid biopsy technologies to detect early HCC markers by identifying specific blood signatures using TET-assisted pyridine borane sequencing (TAPS) assays on cell-free DNA, identifying proteomic/metabolomic signatures using metabolic and proteomic assays and finding a potential relation between blood and metabolic/proteomic markers. In addition, the work package will verify the presence known Auto-Antibodies specific to HCC.