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Chunxiao Song

Chunxiao is a PI at the Ludwig Institute for Cancer Research, University of Oxford. His lab develops novel technologies in epigenetics and applying them to elucidate epigenetic mechanisms in tumour biology and develop clinical applications in epigenetics. In the DeLIVER program he will apply the recently developed bisulfite-free and base-resolution DNA epigenetic sequencing method, TAPS (TET-assisted pyridine borane sequencing), to sequence DNA methylation in HCC patient samples, including tumour tissue DNA, as well as circulating cell-free DNA from blood in the form of liquid biopsies. He will extract genetic and epigenetic information from the dataset, perform molecular analysis and integrate with other datasets that will be generated in the program, to improve the early detection of HCC.