Dear DeLIVER Research Teams,
2000 participants recruited to the Pearl Study!!
We’re thrilled to announce that the 2000th participant has been recruited to the Pearl study recently. This is a significant milestone for the study, and we remain deeply grateful for all your dedication and hard work in achieving this.
As we discussed during our last sites catch-up meeting, if each of our 43 sites recruits just 4 participants per month, we meet our overall target of 3000 by the current recruitment end date of 30th April. There will be a prize for all sites that rise to the challenge😊. Thank you to the sites that have already stepped up their recruitment efforts.
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The Pearl Study Recruitment to date: 2034/3000 Follow up visits completed: 764
HCC diagnoses to date: 46 |
The Selina Study Recruitment: 228/250 Follow up visits: 99
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Follow up visits
Follow up visits are also well underway for participants in both the Pearl and Selina studies. We’d like to emphasise how important these are to the success of the studies. Serial sample collection plays a vital role in identifying biomarkers that could enable earlier diagnosis of HCC or help identify those at higher risk of HCC in the future. Your ongoing commitment to these follow ups is essential to the success of our studies.
Christmas Sample Processing
As Christmas approaches, we’re pleased to confirm that the Oxford lab will remain open and you can continue recruitment and sample collection to the DeLIVER studies as normal.
The cfDNA tubes have a stability window of up to 10 days and a member of the Oxford lab team will be working between Christmas and New Year. This means that any samples taken during that time should be received and processed within this 10-day timeframe. Please ensure that the cfDNA shipping form is completed in REDCap on the day the samples are shipped as this will allow us to track what samples might be expected over this period.
As a heads up – we are still pulling together a newsletter for patients in the study, that we hope you can help us distribute in the new year – and have a liver cancer information evening for patients (and anyone else interested) planned for May 15th 5-6 pm 2025 (watch this space).
In terms of science – the focus in the year will be on data generation from the samples, including GAAD, TAPS, genetic, and metabolomic analysis. We will also publish a description of the cohort as soon as we are fully recruited – so next year we will hopefully really start to see some rewards from our, and your years of hard work
Wishing You a Wonderful Holiday Season
Thank you once again for your incredible efforts this year. We wish you all a Merry Christmas and a Happy New Year and look forward to seeing you at our next catch-up meeting on 14th January 2025 – invites have been sent but please contact Jenni if you have not received one.
Kind Regards
Ellie, Emily, Jenni and James